Natural human interferon-α2 is O-glycosylated
نویسندگان
چکیده
منابع مشابه
Properties of non-glycosylated human interferon-beta from MG63 cells.
MG63 cells induced by Sendai virus produce human interferon (IFN)-beta with a molecular weight of 22000. In the presence of tunicamycin, they produced non-glycosylated, biologically active, IFN-beta with a molecular weight of 17000. It had slightly lower heat stability (at 56 degrees C) than normal glycosylated IFN, but the sensitivity to neutralization by antisera and the cross-species activit...
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Protein O-linked mannose β1,2-N-acetylglucosaminyltransferase 1 (POMGNT1) is a Golgi glycosyltransferase that catalyzes the formation of the N-acetylglucosamine (GlcNAc) β1→2Man linkage of O-mannosyl glycan. POMGNT1 is not modified by N-glycans because there are no potential N-glycosylation sites; however, it is not clear whether POMGNT1 is modified by O-glycans. To determine whether POMGNT1 is...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1991
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj2760511